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Angiotensin IV

CAS No. 12676-15-2

Angiotensin IV( Angiotensin II (3-8) human? )

Catalog No. M20638 CAS No. 12676-15-2

Angiotensin IV is a less effective agonist at the angiotensin AT1 receptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Angiotensin IV
  • Note
    Research use only, not for human use.
  • Brief Description
    Angiotensin IV is a less effective agonist at the angiotensin AT1 receptor.
  • Description
    Angiotensin IV is a less effective agonist at the angiotensin AT1 receptor.
  • In Vitro
    ——
  • In Vivo
    Human Angiotensin II (3-8) causes endothelium-dependent renal cortical vasodilatation, in anaesthetized rats. At doses up to 125 pmol/kg, human Angiotensin II (3-8) is without any cardiovascular effects, but with doses of 1.25 and 12.5 nmol/kg there are dose-dependent increases in mean arterial blood pressure and reductions in renal and mesenteric flows and vascular conductances.
  • Synonyms
    Angiotensin II (3-8) human?
  • Pathway
    Endocrinology/Hormones
  • Target
    RAAS
  • Recptor
    angiotensin AT1 receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    12676-15-2
  • Formula Weight
    774.91
  • Molecular Formula
    C40H54N8O8
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wang QG Xue X Yang Yet al.Angiotensin IV suppresses inflammation in the brains of rats with chronic cerebral hypoperfusion[J].J Renin Angiotensin Aldosterone Syst. 2018 Jul-Sep;19(3):1470320318799587.
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